Being flexible: the voltage-controllable activation gate of Kv channels
Kv channels form voltage-dependent potassium selective pores in the outer cell membrane and are composed out of four -subunits, each having six membrane-spanning -helices (S1-S6). The -subunits tetramerize such that the S5-S6 pore domains co-assemble into a centrally located K+ pore which is surr...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2012-09-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphar.2012.00168/full |