Pharmacogenetics and predictive testing of drug hypersensitivity reactions

Adverse drug reactions ADR occur in approximately 17% of patients. Avoiding ADR is thus mandatory from both an ethical and an economic point of view. Whereas pharmacogenetics changes of the pharmacokinetics may contribute to the explanation of some type A reactions, strong relationships of genetic m...

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Bibliographic Details
Main Authors: Ruwen Boehm, Ingolf Cascorbi
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00396/full