High prevalence of drug resistance in animal trypanosomes without a history of drug exposure.

BACKGROUND:Trypanosomosis caused by Trypanosoma congolense is a major constraint to animal health in sub-Saharan Africa. Unfortunately, the treatment of the disease is impaired by the spread of drug resistance. Resistance to diminazene aceturate (DA) in T. congolense is linked to a mutation modifyin...

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Bibliographic Details
Main Authors: Simbarashe Chitanga, Tanguy Marcotty, Boniface Namangala, Peter Van den Bossche, Jan Van Den Abbeele, Vincent Delespaux
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-12-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22206039/pdf/?tool=EBI