Importance of the origin of mesenchymal (stem) stromal cells in cancer biology: “alliance” or “war” in intercellular signals

Abstract Mesenchymal stem cells (MSCs) play a central role in the intercellular signaling within the tumor microenvironment (TME), exchanging signals with cancer cells and tumor stromal cells, such as cancer-associated fibroblasts and inflammatory mononuclear cells. Research attributes both pro-tumo...

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Bibliographic Details
Main Authors: Noemi Eiro, Maria Fraile, Silvia Fernández-Francos, Rosario Sánchez, Luis A. Costa, Francisco J. Vizoso
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Cell & Bioscience
Subjects:
Online Access:https://doi.org/10.1186/s13578-021-00620-6