The mTORC1/eIF4E/HIF-1α Pathway Mediates Glycolysis to Support Brain Hypoxia Resistance in the Gansu Zokor, Eospalax cansus

The mTORC1/eIF4E/HIF-1α Pathway Mediates Glycolysis to Support Brain Hypoxia Resistance in the Gansu Zokor, Eospalax cansus

The Gansu zokor (Eospalax cansus) is a subterranean rodent species that is unique to China. These creatures inhabit underground burrows with a hypoxia environment. Metabolic energy patterns in subterranean rodents have become a recent focus of research; however, little is known about brain energy me...

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Bibliographic Details
Main Authors: Jinyan Lin, Lele Fan, Yuming Han, Juanjuan Guo, Zhiqiang Hao, Lingna Cao, Jiamin Kang, Xiaoqin Wang, Jianping He, Jingang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Physiology
Subjects:
brain
hypoxia
mTORC1
fructose-driven glycolysis
Gansu zokor (Eospalax cansus)
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.626240/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.626240/full

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