A human endogenous retrovirus encoded protease potentially cleaves numerous cellular proteins

A human endogenous retrovirus encoded protease potentially cleaves numerous cellular proteins

Abstract Background A considerable portion of the human genome derives from retroviruses inherited over millions of years. Human endogenous retroviruses (HERVs) are usually severely mutated, yet some coding-competent HERVs exist. The HERV-K(HML-2) group includes evolutionarily young proviruses that...

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Bibliographic Details
Main Authors: Giuseppe Rigogliuso, Martin L. Biniossek, John L. Goodier, Bettina Mayer, Gavin C. Pereira, Oliver Schilling, Eckart Meese, Jens Mayer
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Mobile DNA
Subjects:
HERV-K
Endogenous retrovirus
Retroviral protease
Proteolysis
Pathogenesis
Retrotransposon
Online Access:http://link.springer.com/article/10.1186/s13100-019-0178-z

Internet

http://link.springer.com/article/10.1186/s13100-019-0178-z

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