Accurate Quantification of AAV Vector Genomes by Quantitative PCR

The ability to accurately determine the dose of an adeno-associated viral (AAV) therapeutic vector is critical to the gene therapy process. Quantitative PCR (qPCR) is one of the common methods to quantify the AAV vector titre, but different variables can lead to inconsistent results. The aim of this...

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Bibliographic Details
Main Authors: Cristina Martinez-Fernandez de la Camara, Michelle E. McClements, Robert E. MacLaren
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/12/4/601