Cerebrospinal fluid (CSF) biomarkers of iron status are associated with CSF viral load, antiretroviral therapy, and demographic factors in HIV-infected adults

Abstract Background HIV-associated neurocognitive disorder (HAND) remains common, despite antiretroviral therapy (ART). HIV dysregulates iron metabolism, but cerebrospinal fluid (CSF) levels of iron and iron-transport proteins in HIV-infected (HIV+) persons are largely unknown. The objectives of thi...

Full description

Bibliographic Details
Main Authors: Stephanie M. Patton, Quan Wang, Todd Hulgan, James R. Connor, Peilin Jia, Zhongming Zhao, Scott L. Letendre, Ronald J. Ellis, William S. Bush, David C. Samuels, Donald R. Franklin, Harpreet Kaur, Jennifer Iudicello, Igor Grant, Asha R. Kallianpur
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Fluids and Barriers of the CNS
Subjects:
HIV
Online Access:http://link.springer.com/article/10.1186/s12987-017-0058-1