Microtubules soften due to cross-sectional flattening

We use optical trapping to continuously bend an isolated microtubule while simultaneously measuring the applied force and the resulting filament strain, thus allowing us to determine its elastic properties over a wide range of applied strains. We find that, while in the low-strain regime, microtubul...

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Bibliographic Details
Main Authors: Edvin Memet, Feodor Hilitski, Margaret A Morris, Walter J Schwenger, Zvonimir Dogic, L Mahadevan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/34695