Shifting the circadian rhythm of feeding in mice induces gastrointestinal, metabolic and immune alterations which are influenced by ghrelin and the core clock gene Bmal1.

<h4>Background</h4>In our 24-hour society, an increasing number of people are required to be awake and active at night. As a result, the circadian rhythm of feeding is seriously compromised. To mimic this, we subjected mice to restricted feeding (RF), a paradigm in which food availabilit...

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Bibliographic Details
Main Authors: Jorien Laermans, Charlotte Broers, Kelly Beckers, Laurien Vancleef, Sandra Steensels, Theo Thijs, Jan Tack, Inge Depoortere
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0110176