Dasatinib synergizes with JSI-124 to inhibit growth and migration and induce apoptosis of malignant human glioma cells

Dasatinib synergizes with JSI-124 to inhibit growth and migration and induce apoptosis of malignant human glioma cells

<b>Background:</b> Src family kinases (SFK) collectively regulate a variety of cellular functions in many cancer types, including proliferation, invasion, motility, survival, differentiation, and angiogenesis. Although Dasatinib (BMS-354825), an ATP-competitive, small molecule tyrosine...

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Bibliographic Details
Main Authors: Premkumar Daniel, Jane Esther, Agostino Naomi, Scialabba Joseph, Pollack Ian
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2010-01-01
Series:Journal of Carcinogenesis
Subjects:
Apoptosis
dasatinib
glioma
JSI - 124
migration
Online Access:http://www.carcinogenesis.com/article.asp?issn=1477-3163;year=2010;volume=9;issue=1;spage=7;epage=7;aulast=Premkumar

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http://www.carcinogenesis.com/article.asp?issn=1477-3163;year=2010;volume=9;issue=1;spage=7;epage=7;aulast=Premkumar

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