Halogen-Substituted Derivatives of <i>Dictyostelium</i> Differentiation-Inducing Factor-1 Suppress Serum-Induced Cell Migration of Human Breast Cancer MDA-MB-231 Cells in Vitro

Halogen-Substituted Derivatives of <i>Dictyostelium</i> Differentiation-Inducing Factor-1 Suppress Serum-Induced Cell Migration of Human Breast Cancer MDA-MB-231 Cells in Vitro

Triple-negative breast cancer (TNBC) is highly proliferative and metastatic, and because it lacks three major molecular targets for chemotherapy (estrogen receptor, progesterone receptor, and human epidermal receptor 2), it is extremely refractory. Differentiation-inducing factor 1 (DIF-1) and DIF-3...

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Bibliographic Details
Main Authors: Kyoko Totsuka, Yuka Makioka, Kyoichi Iizumi, Katsunori Takahashi, Yoshiteru Oshima, Haruhisa Kikuchi, Yuzuru Kubohara
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Biomolecules
Subjects:
triple-negative breast cancer
metastasis
cell migration
anticancer drug
<i>Dictyostelium discoideum</i>
DIF
Online Access:https://www.mdpi.com/2218-273X/9/7/256

Internet

https://www.mdpi.com/2218-273X/9/7/256

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