CCR1 plays a critical role in modulating pain through hematopoietic and non-hematopoietic cells.

CCR1 plays a critical role in modulating pain through hematopoietic and non-hematopoietic cells.

Inflammation is associated with immune cells infiltrating into the inflammatory site and pain. CC chemokine receptor 1 (CCR1) mediates trafficking of leukocytes to sites of inflammation. However, the contribution of CCR1 to pain is incompletely understood. Here we report an unexpected discovery that...

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Bibliographic Details
Main Authors: Nuruddeen D Lewis, Akalushi Muthukumarana, Steven E Fogal, Laura Corradini, Dimitria E Stefanopoulos, Prathima Adusumalli, Josephine Pelletier, Mark Panzenbeck, Karen Berg, Melissa Canfield, Brian N Cook, Hossein Razavi, Daniel Kuzmich, Shawn Anderson, Devan Allard, Paul Harrison, Christine Grimaldi, Donald Souza, Christian Harcken, Ryan M Fryer, Louise K Modis, Maryanne L Brown
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4149507?pdf=render

Internet

http://europepmc.org/articles/PMC4149507?pdf=render

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