The CLIP-domain serine protease homolog SPCLIP1 regulates complement recruitment to microbial surfaces in the malaria mosquito Anopheles gambiae.
The complement C3-like protein TEP1 of the mosquito Anopheles gambiae is required for defense against malaria parasites and bacteria. Two forms of TEP1 are present in the mosquito hemolymph, the full-length TEP1-F and the proteolytically processed TEP1(cut) that is part of a complex including the le...
Main Authors: | Michael Povelones, Lavanya Bhagavatula, Hassan Yassine, Lee Aun Tan, Leanna M Upton, Mike A Osta, George K Christophides |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
|
Series: | PLoS Pathogens |
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24039584/pdf/?tool=EBI |
Similar Items
-
The CLIP-domain serine protease CLIPC9 regulates melanization downstream of SPCLIP1, CLIPA8, and CLIPA28 in the malaria vector Anopheles gambiae.
by: Gregory L Sousa, et al.
Published: (2020-10-01) -
Structure-function analysis of the Anopheles gambiae LRIM1/APL1C complex and its interaction with complement C3-like protein TEP1.
by: Michael Povelones, et al.
Published: (2011-04-01) -
The mosquito melanization response requires hierarchical activation of non-catalytic clip domain serine protease homologs.
by: Layla El Moussawi, et al.
Published: (2019-11-01) -
An epithelial serine protease, AgESP, is required for Plasmodium invasion in the mosquito Anopheles gambiae.
by: Janneth Rodrigues, et al.
Published: (2012-01-01) -
Comprehensive genetic dissection of the hemocyte immune response in the malaria mosquito Anopheles gambiae.
by: Fabrizio Lombardo, et al.
Published: (2013-01-01)