The Effects of Shiga Toxin 1, 2 and Their Subunits on Cytokine and Chemokine Expression by Human Macrophage-Like THP-1 Cells
Infection by Shiga toxin (Stx)-producing enterohemorrhagic Escherichia coli (EHEC) results in severe diarrhea, hemorrhagic colitis, and, occasionally, hemolytic-uremic syndrome (HUS). HUS is associated with an increase in pro-inflammatory cytokines and chemokines, many of which are produced by macro...
Main Authors: | Jeremy R. Brandelli, Thomas P. Griener, Austin Laing, George Mulvey, Glen D. Armstrong |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2015-10-01
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Series: | Toxins |
Subjects: | |
Online Access: | http://www.mdpi.com/2072-6651/7/10/4054 |
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