IL-17/miR-192/IL-17Rs regulatory feedback loop facilitates multiple myeloma progression.

Multiple myeloma (MM) is a clonal plasma cell disorder which constitutes the second most common hematological malignancy, and remains an incurable tumor with poor survival. Recently, interleukin-17 (IL-17), produced locally in the tumor microenvironment, has been reported to play a crucial role in t...

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Bibliographic Details
Main Authors: Yuanyuan Sun, Jing Pan, Shudan Mao, Jieping Jin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4260882?pdf=render