NOTCH Signaling Controls Ciliary Body Morphogenesis and Secretion by Directly Regulating Nectin Protein Expression

NOTCH Signaling Controls Ciliary Body Morphogenesis and Secretion by Directly Regulating Nectin Protein Expression

Summary: Anterior segment dysgenesis is often associated with cornea diseases, cataracts, and glaucoma. In the anterior segment, the ciliary body (CB) containing inner and outer ciliary epithelia (ICE and OCE) secretes aqueous humor that maintains intraocular pressure (IOP). However, CB development...

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Bibliographic Details
Main Authors: Ji Pang, Liang Le, Yi Zhou, Renjun Tu, Qiang Hou, Dai Tsuchiya, Nancy Thomas, Yongfu Wang, Zulin Yu, Richard Alexander, Marina Thexton, Brandy Lewis, Timothy Corbin, Michael Durnin, Hua Li, Ruth Ashery-Padan, Deyue Yan, Ting Xie
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Cell Reports
Subjects:
ciliary body
NOTCH signaling
Nectin1
Cx43
viteous
aqueous humor
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720315928

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http://www.sciencedirect.com/science/article/pii/S2211124720315928

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