Sedative and Immunosuppressive Effects of Dexmedetomidine in Transplantation

Dexmedetomidine, an α2-adrenergic receptor agonist, is used as an anti-anxiety medication. It exerts a cholinergic effect, thereby reducing the release of tumor necrosis factor alpha (TNF-α). We hypothesized that the use of dexmedetomidine as a sedative agent in transplantation would also protect al...

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Bibliographic Details
Main Authors: Chen-Fang Lee, Chih-Hsien Cheng, Hao-Chien Hung, Jin-Chiao Lee, Yu-Chiao Wang, Tsung-Han Wu, Ting-Jung Wu, Hong-Shiue Chou, Kun-Ming Chan, Wei-Chen Lee
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/14/8/825