Long-term endogenous acetylcholine deficiency potentiates pulmonary inflammation in a murine model of elastase-induced emphysema

Long-term endogenous acetylcholine deficiency potentiates pulmonary inflammation in a murine model of elastase-induced emphysema

Abstract Acetylcholine (ACh), the neurotransmitter of the cholinergic system, regulates inflammation in several diseases including pulmonary diseases. ACh is also involved in a non-neuronal mechanism that modulates the innate immune response. Because inflammation and release of pro-inflammatory cyto...

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Bibliographic Details
Main Authors: Rosana Banzato, Nathalia M. Pinheiro, Clarice R. Olivo, Fernanda R. Santana, Fernanda D. T. Q. S. Lopes, Luciana C. Caperuto, Niels O. Câmara, Milton A. Martins, Iolanda F. L. C. Tibério, Marco Antônio M. Prado, Vânia F. Prado, Carla M. Prado
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95211-3

Internet

https://doi.org/10.1038/s41598-021-95211-3

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