Causal reasoning identifies mechanisms of sensitivity for a novel AKT kinase inhibitor, GSK690693

Causal reasoning identifies mechanisms of sensitivity for a novel AKT kinase inhibitor, GSK690693

<p>Abstract</p> <p>Background</p> <p>Inappropriate activation of AKT signaling is a relatively common occurrence in human tumors, and can be caused by activation of components of, or by loss or decreased activity of inhibitors of, this signaling pathway. A novel, pan AK...

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Bibliographic Details
Main Authors: Macoritto Michael, Pratt Dexter, Petricoin Emanuel F, Ellis Catherine E, Blakemore Stephen J, Kumar Rakesh, Matthews Andrea L, Loureiro Joseph J, Elliston Keith
Format: Article
Language:English
Published: BMC 2010-07-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/11/419

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http://www.biomedcentral.com/1471-2164/11/419

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