Activin A Signaling Regulates IL13Rα2 Expression to Promote Breast Cancer Metastasis

Activin A Signaling Regulates IL13Rα2 Expression to Promote Breast Cancer Metastasis

Metastatic dissemination of cancer cells to distal organs is the major cause of death for patients suffering from the aggressive basal-like breast cancer (BLBC) subtype. Recently, we have shown that interleukin 13 receptor alpha 2 (IL13Rα2) is a critical gene that is overexpressed in a subset of BLB...

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Bibliographic Details
Main Authors: Maria Kalli, Fotios Mpekris, Chen K. Wong, Myrofora Panagi, Sait Ozturk, Sam Thiagalingam, Triantafyllos Stylianopoulos, Panagiotis Papageorgis
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Oncology
Subjects:
Activin A
breast cancer
migration
metastasis
IL13Rα2
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2019.00032/full

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https://www.frontiersin.org/article/10.3389/fonc.2019.00032/full

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