STAT3 Relays a Differential Response to Melanoma-Associated <i>NRAS</i> Mutations

Melanoma patients carrying an oncogenic <i>NRAS</i> mutation represent 20% of all cases and present worse survival, relapse rate and therapy response than patients with wild type <i>NRAS</i> or with <i>BRAF</i> mutations. Nevertheless, no efficient targeted therap...

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Bibliographic Details
Main Authors: James Kim, Daniel Novak, Christos Sachpekidis, Jochen Utikal, Lionel Larribère
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/12/1/119