The Functional Role of the 3′ Untranslated Region and Poly(A) Tail of Duck Hepatitis A Virus Type 1 in Viral Replication and Regulation of IRES-Mediated Translation

The Functional Role of the 3′ Untranslated Region and Poly(A) Tail of Duck Hepatitis A Virus Type 1 in Viral Replication and Regulation of IRES-Mediated Translation

The duck hepatitis A virus type 1 (DHAV-1) is a member of Picornaviridae family, the genome of the virus contains a 5′ untranslated region (5′ UTR), a large open reading frame that encodes a polyprotein precursor and a 3′ UTR followed by a poly(A) tail. The translation initiation of virus proteins d...

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Bibliographic Details
Main Authors: Jun-Hao Chen, Rui-Hua Zhang, Shao-Li Lin, Peng-Fei Li, Jing-Jing Lan, Sha-Sha Song, Ji-Ming Gao, Yu Wang, Zhi-Jing Xie, Fu-Chang Li, Shi-Jin Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Microbiology
Subjects:
DHAV-1
3′ UTR
poly(A) tail
viral replication
IRES-mediated translation
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2018.02250/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2018.02250/full

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