Location, location, location: the impact of migratory heterogeneity on T cell function

T cell migration is crucial for an effective adaptive immune response to invading pathogens. Naive and memory T cells encounter pathogen antigens, become activated and differentiate into effector cells in secondary lymphoid tissues, and then migrate to the site(s) of infection where they exert effec...

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Bibliographic Details
Main Authors: Bas J Baaten, Andrea M Cooper, Susan L Swain, Linda M Bradley
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00311/full