Nox4 Expression Is Not Required for OVX‐Induced Osteoblast Senescence and Bone Loss in Mice

ABSTRACT Estrogen deficiency and aging play critical roles in the pathophysiology of bone as a result of increased oxidative stress. It has been suggested that prevention of NADPH oxidase‐ (Nox‐) dependent accumulation of ROS may be an approach to potentially minimize bone loss caused by these condi...

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Bibliographic Details
Main Authors: Jin‐Ran Chen, Oxana P Lazarenko, Haijun Zhao, Umesh D Wankhade, Kim Pedersen, James Watt, Martin J J Ronis
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:JBMR Plus
Subjects:
Online Access:https://doi.org/10.1002/jbm4.10376