NAMPT overexpression alleviates alcohol-induced hepatic steatosis in mice.

NAMPT overexpression alleviates alcohol-induced hepatic steatosis in mice.

Nicotinamide phosphoribosyltransferase (NAMPT) is a rate-limiting enzyme in mammalian nicotinamide adenine dinucleotide (NAD)+ biosynthesis. Through its NAD+-biosynthetic activity, NAMPT influences the activity of NAD+-dependent enzymes, such as sirtuins. NAMPT is able to modulate processes involved...

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Bibliographic Details
Main Authors: Xiwen Xiong, Jiahui Yu, Rui Fan, Cuicui Zhang, Lin Xu, Xupeng Sun, Yanmei Huang, Qingzhi Wang, Hai-Bin Ruan, Xinlai Qian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0212523

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https://doi.org/10.1371/journal.pone.0212523

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