A conserved RNA degradation complex required for spreading and epigenetic inheritance of heterochromatin

A conserved RNA degradation complex required for spreading and epigenetic inheritance of heterochromatin

Heterochromatic domains containing histone H3 lysine 9 methylation (H3K9me) can be epigenetically inherited independently of underlying DNA sequence. To gain insight into the mechanisms that mediate epigenetic inheritance, we used a Schizosaccharomyces pombe inducible heterochromatin formation syste...

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Bibliographic Details
Main Authors: Gergana Shipkovenska, Alexander Durango, Marian Kalocsay, Steven P Gygi, Danesh Moazed
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-06-01
Series:eLife
Subjects:
heterochromatin
epigenetics
RNA degradation
H3K9 methylation
Rix1
rixosome
Online Access:https://elifesciences.org/articles/54341

Internet

https://elifesciences.org/articles/54341

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