Interferon antagonism by SARS-CoV-2: a functional study using reverse genetics

Summary: Background: The COVID-19 agent, SARS-CoV-2, is conspecific with SARS-CoV, the causal agent of the severe acute respiratory syndrome epidemic in 2002–03. Although the viruses share a completely homologous repertoire of proteins and use the same cellular entry receptor, their transmission ef...

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Bibliographic Details
Main Authors: Simon Schroeder, MSc, Fabian Pott, MSc, Daniela Niemeyer, PhD, Talitha Veith, MPhil, Anja Richter, Doreen Muth, PhD, Christine Goffinet, ProfPhD, Marcel A Müller, PhD, Christian Drosten, ProfPhD
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:The Lancet Microbe
Online Access:http://www.sciencedirect.com/science/article/pii/S2666524721000276