Sinusoidal endothelial dysfunction precedes inflammation and fibrosis in a model of NAFLD.

Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome. Most morbidity associated with the metabolic syndrome is related to vascular complications, in which endothelial dysfunction is a major pathogenic factor. However, whether NAFLD is associated with endot...

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Bibliographic Details
Main Authors: Marcos Pasarín, Vincenzo La Mura, Jorge Gracia-Sancho, Héctor García-Calderó, Aina Rodríguez-Vilarrupla, Juan Carlos García-Pagán, Jaime Bosch, Juan G Abraldes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3317918?pdf=render