KVarPredDB: a database for predicting pathogenicity of missense sequence variants of keratin genes associated with genodermatoses

KVarPredDB: a database for predicting pathogenicity of missense sequence variants of keratin genes associated with genodermatoses

Abstract Background Germline variants of ten keratin genes (K1, K2, K5, K6A, K6B, K9, K10, K14, K16, and K17) have been reported for causing different types of genodermatoses with an autosomal dominant mode of inheritance. Among all the variants of these ten keratin genes, most of them are missense...

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Bibliographic Details
Main Authors: Yuyi Ying, Lu Lu, Santasree Banerjee, Lizhen Xu, Qiang Zhao, Hao Wu, Ruiqi Li, Xiao Xu, Hua Yu, Dante Neculai, Yongmei Xi, Fan Yang, Jiale Qin, Chen Li
Format: Article
Language:English
Published: BMC 2020-12-01
Series:Human Genomics
Subjects:
Keratin genes
Genodermatoses
Pathogenicity
Missense variants
Novel variants
Database
Online Access:https://doi.org/10.1186/s40246-020-00295-z

Internet

https://doi.org/10.1186/s40246-020-00295-z

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