Excessive Production of Transforming Growth Factor β1 Causes Mural Cell Depletion From Cerebral Small Vessels

Excessive Production of Transforming Growth Factor β1 Causes Mural Cell Depletion From Cerebral Small Vessels

It is increasingly becoming apparent that cerebrovascular dysfunction contributes to the pathogenic processes involved in vascular dementia, Alzheimer’s disease, and other neurodegenerative disorders. Under these pathologic conditions, the degeneration of cerebral blood vessels is frequently accompa...

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Bibliographic Details
Main Authors: Taisuke Kato, Yumi Sekine, Hiroaki Nozaki, Masahiro Uemura, Shoichiro Ando, Sachiko Hirokawa, Osamu Onodera
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Aging Neuroscience
Subjects:
TGFβ
mural cells
smooth muscle cells
pericytes
cerebral small vessel
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2020.00151/full

Internet

https://www.frontiersin.org/article/10.3389/fnagi.2020.00151/full

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