GDNF and GFRα1 Are Required for Proper Integration of Adult-Born Hippocampal Neurons

Summary: The glial cell line-derived neurotrophic factor (GDNF) is required for the survival and differentiation of diverse neuronal populations during nervous system development. Despite the high expression of GDNF and its receptor GFRα1 in the adult hippocampus, the functional role of this system...

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Bibliographic Details
Main Authors: Antonela Bonafina, Mariela Fernanda Trinchero, Antonella Soledad Ríos, Pedro Bekinschtein, Alejandro Fabián Schinder, Gustavo Paratcha, Fernanda Ledda
Format: Article
Language:English
Published: Elsevier 2019-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719316006