Evolutionary relationships of Aurora kinases: Implications for model organism studies and the development of anti-cancer drugs

<p>Abstract</p> <p>Background</p> <p>As key regulators of mitotic chromosome segregation, the Aurora family of serine/threonine kinases play an important role in cell division. Abnormalities in Aurora kinases have been strongly linked with cancer, which has lead to the...

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Bibliographic Details
Main Authors: Patrick Denis R, Sanseau Philippe, Birkeland Marian L, Koretke Kristin K, Brown James R
Format: Article
Language:English
Published: BMC 2004-10-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/4/39