Plant-Produced Receptor-Binding Domain of SARS-CoV-2 Elicits Potent Neutralizing Responses in Mice and Non-human Primates

Plant-Produced Receptor-Binding Domain of SARS-CoV-2 Elicits Potent Neutralizing Responses in Mice and Non-human Primates

The emergence of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected global public health and economy. Despite the substantial efforts, only few vaccines are currently approved and some are in the different stages of clinical trials...

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Main Authors: Konlavat Siriwattananon, Suwimon Manopwisedjaroen, Balamurugan Shanmugaraj, Kaewta Rattanapisit, Supaporn Phumiamorn, Sompong Sapsutthipas, Sakalin Trisiriwanich, Eakachai Prompetchara, Chutitorn Ketloy, Supranee Buranapraditkun, Wassana Wijagkanalan, Kittipan Tharakhet, Papatsara Kaewpang, Kantinan Leetanasaksakul, Taratorn Kemthong, Nutchanat Suttisan, Suchinda Malaivijitnond, Kiat Ruxrungtham, Arunee Thitithanyanont, Waranyoo Phoolcharoen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Plant Science
Subjects:
COVID-19
SARS-CoV-2
receptor-binding domain
Nicotiana benthamiana
plant-produced recombinant protein
Fc fusion protein
Online Access:https://www.frontiersin.org/articles/10.3389/fpls.2021.682953/full

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https://www.frontiersin.org/articles/10.3389/fpls.2021.682953/full

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