Protection of Oligodendrocytes Through Neuronal Overexpression of the Small GTPase Ras in Hyperoxia-Induced Neonatal Brain Injury

Protection of Oligodendrocytes Through Neuronal Overexpression of the Small GTPase Ras in Hyperoxia-Induced Neonatal Brain Injury

Prematurely born infants are highly susceptible to various environmental factors, such as inflammation, drug exposure, and also high environmental oxygen concentrations. Hyperoxia induces perinatal brain injury affecting white and gray matter development. It is well known that mitogen-activated prot...

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Bibliographic Details
Main Authors: Meray Serdar, Josephine Herz, Karina Kempe, Elke Winterhager, Holger Jastrow, Rolf Heumann, Ursula Felderhoff-Müser, Ivo Bendix
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-03-01
Series:Frontiers in Neurology
Subjects:
preterm birth
brain injury
hyperoxia
neuronal Ras
white matter injury
neuroprotection
Online Access:http://journal.frontiersin.org/article/10.3389/fneur.2018.00175/full

Internet

http://journal.frontiersin.org/article/10.3389/fneur.2018.00175/full

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