Impaired autoimmune T helper 17 cell responses following DNA vaccination against rat experimental autoimmune encephalomyelitis.

Impaired autoimmune T helper 17 cell responses following DNA vaccination against rat experimental autoimmune encephalomyelitis.

BACKGROUND: We have previously shown that vaccination with DNA encoding the encephalitogenic peptide myelin oligodendrocyte glycoprotein (MOG)(91-108) (pMOG) suppresses MOG(91-108)-induced rat Experimental Autoimmune Encephalomyelitis (EAE), a model for human Multiple Sclerosis (MS). The suppressive...

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Bibliographic Details
Main Authors: Asa Andersson, Magnus Isaksson, Judit Wefer, Anna Norling, Amilcar Flores-Morales, Fredrik Rorsman, Olle Kämpe, Robert A Harris, Anna Lobell
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2008-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2577303?pdf=render

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http://europepmc.org/articles/PMC2577303?pdf=render

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