HPV16 E6 and E7 Upregulate Interferon-Induced Antiviral Response Genes ISG15 and IFIT1 in Human Trophoblast Cells

HPV16 E6 and E7 Upregulate Interferon-Induced Antiviral Response Genes ISG15 and IFIT1 in Human Trophoblast Cells

Human papillomavirus (HPV) is suggested to infect trophoblasts in the placenta, and HPV infections are reported to be more prevalent in pregnancies with adverse outcomes. Results are however controversial, and studies investigating the molecular consequences of placental HPV infections are lacking....

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Bibliographic Details
Main Authors: Lea M.M. Ambühl, Annemarie B. Villadsen, Ulrik Baandrup, Karen Dybkær, Suzette Sørensen
Format: Article
Language:English
Published: MDPI AG 2017-09-01
Series:Pathogens
Subjects:
human papillomavirus
trophoblast cell
placenta
interferon
antiviral response
Online Access:https://www.mdpi.com/2076-0817/6/3/40

Internet

https://www.mdpi.com/2076-0817/6/3/40

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