Oncolytic Newcastle disease virus delivered by Mesenchymal stem cells-engineered system enhances the therapeutic effects altering tumor microenvironment

Oncolytic Newcastle disease virus delivered by Mesenchymal stem cells-engineered system enhances the therapeutic effects altering tumor microenvironment

Abstract Background Human papillomavirus (HPV)-associated malignancy remain a main cause of cancer in men and women. Cancer immunotherapy has represented great potential as a new promising cancer therapeutic approach. Here, we report Mesenchymal stem cells (MSCs) as a carrier for the delivery of onc...

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Bibliographic Details
Main Authors: Mohsen Keshavarz, Mir Saeed Ebrahimzadeh, Seyed Mohammad Miri, Hassan Dianat-Moghadam, Seyedeh Sara Ghorbanhosseini, Seyed Reza Mohebbi, Hossein Keyvani, Amir Ghaemi
Format: Article
Language:English
Published: BMC 2020-05-01
Series:Virology Journal
Subjects:
Mesenchymal stem cells
Oncolytic Newcastle disease virus
Human papillomavirus
CD8 + 
Tumor microenvironment
Myeloid-derived suppressor cells
Online Access:http://link.springer.com/article/10.1186/s12985-020-01326-w

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http://link.springer.com/article/10.1186/s12985-020-01326-w

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