Synergy in anti-malarial pre-erythrocytic and transmission-blocking antibodies is achieved by reducing parasite density

Synergy in anti-malarial pre-erythrocytic and transmission-blocking antibodies is achieved by reducing parasite density

Anti-malarial pre-erythrocytic vaccines (PEV) target transmission by inhibiting human infection but are currently partially protective. It has been posited, but never demonstrated, that co-administering transmission-blocking vaccines (TBV) would enhance malaria control. We hypothesized a mechanism t...

Full description

Bibliographic Details
Main Authors: Ellie Sherrard-Smith, Katarzyna A Sala, Michael Betancourt, Leanna M Upton, Fiona Angrisano, Merribeth J Morin, Azra C Ghani, Thomas S Churcher, Andrew M Blagborough
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-06-01
Series:eLife
Subjects:
Anopheles stephensi
Plasmodium berghei
transmission-blocking vaccine
synergy
multigenerational population assay
pre-erythrocytic vaccine
Online Access:https://elifesciences.org/articles/35213

Similar Items

Similar Items