Region-based interaction detection in genome-wide case-control studies
Abstract Background In genome-wide association study (GWAS), conventional interaction detection methods such as BOOST are mostly based on SNP-SNP interactions. Although single nucleotides are the building blocks of human genome, single nucleotide polymorphisms (SNPs) are not necessarily the smallest...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-12-01
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Series: | BMC Medical Genomics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12920-019-0583-7 |