The Potential Protective Effect of Curcumin on Amyloid-β-42 Induced Cytotoxicity in HT-22 Cells

Background. We aimed to investigate the effect and mechanism of curcumin (CUR) in Alzheimer’s disease (AD). Methods. Mouse hippocampal neuronal cell line HT-22 was treated with Aβ1–42 and/or CUR, and then cell viability was evaluated by cell counting kit 8, Beclin-l level was detected using western...

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Bibliographic Details
Main Authors: Lu Zhang, Yu Fang, Xuan Cheng, Yajun Lian, Zhaoshu Zeng, Chuanjie Wu, Hongcan Zhu, Hongliang Xu
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2018/8134902