Improved Microbial Community Characterization of 16S rRNA via Metagenome Hybridization Capture Enrichment

Improved Microbial Community Characterization of 16S rRNA via Metagenome Hybridization Capture Enrichment

Environmental microbial diversity is often investigated from a molecular perspective using 16S ribosomal RNA (rRNA) gene amplicons and shotgun metagenomics. While amplicon methods are fast, low-cost, and have curated reference databases, they can suffer from amplification bias and are limited in gen...

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Bibliographic Details
Main Authors: Megan S. Beaudry, Jincheng Wang, Troy J. Kieran, Jesse Thomas, Natalia J. Bayona-Vásquez, Bei Gao, Alison Devault, Brian Brunelle, Kun Lu, Jia-Sheng Wang, Olin E. Rhodes, Travis C. Glenn
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Microbiology
Subjects:
amplicon
microbial diversity
microbiome
mock communities
next generation sequencing
shotgun libraries
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.644662/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2021.644662/full

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