Radioligands for Tropomyosin Receptor Kinase (Trk) Positron Emission Tomography Imaging

Radioligands for Tropomyosin Receptor Kinase (Trk) Positron Emission Tomography Imaging

The tropomyosin receptor kinases family (TrkA, TrkB, and TrkC) supports neuronal growth, survival, and differentiation during development, adult life, and aging. TrkA/B/C downregulation is a prominent hallmark of various neurological disorders including Alzheimer’s disease (AD). Abnormally...

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Bibliographic Details
Main Authors: Ralf Schirrmacher, Justin J. Bailey, Andrew V. Mossine, Peter J. H. Scott, Lena Kaiser, Peter Bartenstein, Simon Lindner, David R. Kaplan, Alexey Kostikov, Gert Fricker, Anne Mahringer, Pedro Rosa-Neto, Esther Schirrmacher, Carmen Wängler, Björn Wängler, Alexander Thiel, Jean-Paul Soucy, Vadim Bernard-Gauthier
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:Pharmaceuticals
Subjects:
tropomyosin receptor kinase
positron emission tomography
neurodegeneration
oncogenic fusions
Online Access:http://www.mdpi.com/1424-8247/12/1/7

Internet

http://www.mdpi.com/1424-8247/12/1/7

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