Elevated IL-33 promotes expression of MMP2 and MMP9 via activating STAT3 in alveolar macrophages during LPS-induced acute lung injury

Elevated IL-33 promotes expression of MMP2 and MMP9 via activating STAT3 in alveolar macrophages during LPS-induced acute lung injury

Abstract Background Pulmonary inflammation and endothelial barrier permeability increase in acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) induced by pro-inflammatory cytokines and matrix metalloproteinases (MMPs). However, the relationship between pro-inflammatory cytokines...

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Bibliographic Details
Main Authors: Yafeng Liang, Nengli Yang, Guoquan Pan, Bingxin Jin, Shufen Wang, Wei Ji
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Cellular & Molecular Biology Letters
Subjects:
Acute lung injury (ALI)
IL-33
MMP2
MMP9
STAT3
Online Access:http://link.springer.com/article/10.1186/s11658-018-0117-x

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http://link.springer.com/article/10.1186/s11658-018-0117-x

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