Precision-mapping and statistical validation of quantitative trait loci by machine learning

<p>Abstract</p> <p>Background</p> <p>We introduce a QTL-mapping algorithm based on Statistical Machine Learning (SML) that is conceptually quite different to existing methods as there is a strong focus on generalisation ability. Our approach combines ridge regression, r...

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Bibliographic Details
Main Authors: Kowalczyk Adam, Wenzl Peter, Bedo Justin, Kilian Andrzej
Format: Article
Language:English
Published: BMC 2008-05-01
Series:BMC Genetics
Online Access:http://www.biomedcentral.com/1471-2156/9/35