The 10-Repeat 3′-UTR VNTR Polymorphism in the SLC6A3 Gene May Confer Protection Against Parkinson’s Disease: A Meta-analysis

The 10-Repeat 3′-UTR VNTR Polymorphism in the SLC6A3 Gene May Confer Protection Against Parkinson’s Disease: A Meta-analysis

The dopamine transporter (DAT) is encoded by the SLC6A3 gene and plays an important role in the regulation of the neurotransmitter dopamine. The SLC6A3 gene contains several repetition alleles (3–11 repeats) of a 40-base pair variable number of tandem repeats (VNTR) in the 3′-untranslated region (3′...

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Bibliographic Details
Main Authors: Qiaoli Zeng, Fan Ning, Shanshan Gu, Qiaodi Zeng, Riling Chen, Liuquan Peng, Dehua Zou, Guoda Ma, Yajun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Genetics
Subjects:
Parkinson’s disease
Slc6a3
dopamine transporter
variable number of tandem repeats
meta-analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.757601/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.757601/full

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