Innovative trial approaches in immune-mediated inflammatory diseases: current use and future potential

Innovative trial approaches in immune-mediated inflammatory diseases: current use and future potential

Abstract Background Despite progress that has been made in the treatment of many immune-mediated inflammatory diseases (IMIDs), there remains a need for improved treatments. Randomised controlled trials (RCTs) provide the highest form of evidence on the effectiveness of a potential new treatment reg...

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Bibliographic Details
Main Authors: Michael J. Grayling, Theophile Bigirumurame, Svetlana Cherlin, Luke Ouma, Haiyan Zheng, James M. S. Wason
Format: Article
Language:English
Published: BMC 2021-07-01
Series:BMC Rheumatology
Subjects:
Adaptive design
Basket design
Bayesian design
Composite endpoint
High-dimensional data
Routinely collected data
Online Access:https://doi.org/10.1186/s41927-021-00192-5

Internet

https://doi.org/10.1186/s41927-021-00192-5

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