Deciphering human heat shock transcription factor 1 regulation via post-translational modification in yeast.

Heat shock transcription factor 1 (HSF1) plays an important role in the cellular response to proteotoxic stresses. Under normal growth conditions HSF1 is repressed as an inactive monomer in part through post-translation modifications that include protein acetylation, sumoylation and phosphorylation....

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Bibliographic Details
Main Authors: Liliana Batista-Nascimento, Daniel W Neef, Phillip C C Liu, Claudina Rodrigues-Pousada, Dennis J Thiele
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3017095?pdf=render