The Distinct Effects of Palmitic and Oleic Acid on Pancreatic Beta Cell Function: The Elucidation of Associated Mechanisms and Effector Molecules

The Distinct Effects of Palmitic and Oleic Acid on Pancreatic Beta Cell Function: The Elucidation of Associated Mechanisms and Effector Molecules

In this study, we aimed to identify the mechanisms underlying the different effects of palmitic acid and oleic acid on human pancreatic beta cell function. To address this problem, the oxidative stress, endoplasmic reticulum stress, inflammation, apoptosis and their mediator molecules have been inve...

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Bibliographic Details
Main Authors: Miruna Nemecz, Alina Constantin, Madalina Dumitrescu, Nicoleta Alexandru, Alexandru Filippi, Gabriela Tanko, Adriana Georgescu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Pharmacology
Subjects:
palmitic acid
oleic acid
human pancreatic beta cells
endoplasmic reticulum stress
inflammation
oxidative stress
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2018.01554/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2018.01554/full

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