Fucans, but not fucomannoglucuronans, determine the biological activities of sulfated polysaccharides from Laminaria saccharina brown seaweed.

Sulfated polysaccharides from Laminaria saccharina (new name: Saccharina latissima) brown seaweed show promising activity for the treatment of inflammation, thrombosis, and cancer; yet the molecular mechanisms underlying these properties remain poorly understood. The aim of this work was to characte...

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Bibliographic Details
Main Authors: Diego O Croci, Albana Cumashi, Natalia A Ushakova, Marina E Preobrazhenskaya, Antonio Piccoli, Licia Totani, Nadezhda E Ustyuzhanina, Maria I Bilan, Anatolii I Usov, Alexey A Grachev, Galina E Morozevich, Albert E Berman, Craig J Sanderson, Maeve Kelly, Patrizia Di Gregorio, Cosmo Rossi, Nicola Tinari, Stefano Iacobelli, Gabriel A Rabinovich, Nikolay E Nifantiev, Consorzio Interuniversitario Nazionale per la Bio-Oncologia (CINBO), Italy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3046160?pdf=render